Linked Life Data

8161443

Source:http://linkedlifedata.com/resource/pubmed/id/8161443

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-5-26
pubmed:abstractText
Use of polymerase chain reaction in HIV monitoring: The polymerase chain reaction can be used not only to detect the presence of viral sequences but also to provide a semiquantitative or a precise evaluation of the number of copies of genome present. Integral to the development of accurate and reproducible assays have been critical advances in polymerase chain reaction technology. In addition, standardization of protocols and reagents has proved invaluable. The HIV life cycle permits both DNA and RNA to be targeted. Although early cross-sectional studies provided little insight into disease progression, recent longitudinal studies have provided valuable information on HIV infection. CONCLUSION: A rapid and simple quantitative assay for HIV RNA in plasma or sera has been developed that should prove valuable in determining the natural history of infection, dissecting viral pathogenesis and monitoring the efficacy of therapeutic intervention.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0269-9370
pubmed:author
pubmed:issnType
Print
pubmed:volume
7 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S29-34
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The application of quantitative polymerase chain reaction to therapeutic monitoring.
pubmed:affiliation
Department of Infectious Diseases, Roche Molecular Systems, Inc., Alameda, California 94501.
pubmed:publicationType
Journal Article, Review