|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
1994-5-16
|
|
pubmed:abstractText |
Endogenous retinoids are potential regulators of vertebrate embryogenesis that have been implicated in early anterior-posterior patterning and limb-bud development. We have characterized the temporal and spatial distribution of 9-cis-retinoic acid in the Xenopus embryo and compared it to two other retinoids, all-trans-retinoic acid and all-trans-retinoyl-beta-glucuronide. 9-cis-Retinoic acid is first detected after the midblastula transition and by the end of gastrulation is localized primarily within the anterior and posterior dorsal regions of the embryo. Since 9-cis-retinoic acid is a 6-fold more potent dysmorphogen than trans-retinoic acid, we suggest that it is involved in the early specification of the Xenopus anterior-posterior axis.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1309942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1310260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1312717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1314386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1326406,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1333659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1347750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1350531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1352213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1438194,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1483395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1528265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1661245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1664231,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1668276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1671660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1678362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1680565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1682132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-17734585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1846602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1907940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-1915273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-2384214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-2561479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-2739735,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-2825025,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-3600758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-4807131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-5014447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-6207484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-6663228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-7070499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8159708-8380496
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0027-8424
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
12
|
|
pubmed:volume |
91
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3067-71
|
|
pubmed:dateRevised |
2010-9-13
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
The retinoid X receptor ligand, 9-cis-retinoic acid, is a potential regulator of early Xenopus development.
|
|
pubmed:affiliation |
Department of Pharmacology, School of Medicine, University of Washington, Seattle 98195.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
