Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1978-12-20
pubmed:abstractText
Sixty-three different antigens of Neisseria meningitidis groups A, B and C were demonstrated by means of crossed immunoelectrophoresis against rabbit antiserum. The group-specific polysaccharides A and C were identified in the immunoprecipitate pattern. The majority of the remaining antigens were common to all three groups of meningococci. A clearcut rise in antibodies was found in all of 27 patients with meningococcal meningitis or septicaemia. These antibodies were directed against both group-specific antigens and common antigens. No such rise was seen among the 22 patients with purulent meningitis of non-meningococcal etiology. Altogether 15 precipitins were detected in the patients with meningococcal disease. Nine of these antibodies could be identified by comparison with the rabbit antiserum. The antibody rise was semiquantified by means of a scoring system. The rise in the precipitin score of antibodies against common antigens in patients infected with group B meningococci was significantly higher than in patients infected with group A meningococci.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0304-1328
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-9
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease.
pubmed:publicationType
Journal Article