Linked Life Data

815863

Source:http://linkedlifedata.com/resource/pubmed/id/815863

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-4-29
pubmed:abstractText
To determine the time of the appearance of cells capable of subsequent synthesis of esterase-6, genital imaginal discs extracted from male larvae of different instars were transplanted in female larvae just before pupation. An analysis of the esterase activity in transplants has shown that cells in which esterase-6 is to be synthesized appear 8-10 hrs after the beginning of the 3rd larval instar, i.e. long before the differentiation starts. The relations between the determination of the gene Est-6 expression and its transcription and translation were assessed by studying the effect of the inhibitors of RNA (actinomycin D) and protein synthesis (cycloheximide). It has been demonstrated that the transcription and translation of the gene Est-6 take place after metamorphosis during the first hours after emergence of imago. There exists, thus, a large interval between the appearance of cells capable of esterase synthesis and the time of expression of the structural gene controlling this enzyme. The data obtained suggest that cell determination may not be due to the accumulation of "long-living" templates (mRNA).
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0475-1450
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
[Determination of gene Est-6 expression in the genitalia of Drosophila melanogaster males].
pubmed:publicationType
Journal Article, English Abstract