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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
301
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pubmed:dateCreated |
1994-5-19
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pubmed:abstractText |
Forty-four patients (46 hips) with infected total hip arthroplasties were evaluated. They were entered into a protocol that included resection arthroplasty, six weeks of intravenous antibiotics which obtained a minimum postpeak serum bactericidal titer of 1:8, and possible reimplantation. Thirty-two of 46 hips (70%) were reimplanted. At an average of 40 months (range, 24-74 months) after reimplantation, infection recurred in three hips (9%). In two of the three recurrent infections, 1:8 bactericidal titers were not attained. Both of these hips were infected with gram-negative organisms. Minimum postpeak serum bactericidal titers of 1:8 were attained in 28 of 32 hips that were reimplanted, and only one of these hips (4%) had a recurrent infection (p = 0.035). The presence of retained cement after resection arthroplasty (ten hips) was not associated with recurrent infection. Fourteen hips (12 patients were not reimplanted as a result of a combination of factors, including inadequate bone stock, poor soft-tissue quality, and antibiotic resistance of the infecting organism. The treatment of an infected total hip arthroplasty with resection arthroplasty, six weeks of intravenous antibiotics that attains a minimum postpeak serum bactericidal titer of 1:8, and reimplantation can be an effective and safe treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0009-921X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-12
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pubmed:dateRevised |
2005-3-3
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pubmed:meshHeading |
pubmed-meshheading:8156676-Adult,
pubmed-meshheading:8156676-Aged,
pubmed-meshheading:8156676-Aged, 80 and over,
pubmed-meshheading:8156676-Anti-Bacterial Agents,
pubmed-meshheading:8156676-Female,
pubmed-meshheading:8156676-Follow-Up Studies,
pubmed-meshheading:8156676-Hip Prosthesis,
pubmed-meshheading:8156676-Humans,
pubmed-meshheading:8156676-Infusions, Intravenous,
pubmed-meshheading:8156676-Male,
pubmed-meshheading:8156676-Microbial Sensitivity Tests,
pubmed-meshheading:8156676-Middle Aged,
pubmed-meshheading:8156676-Postoperative Complications,
pubmed-meshheading:8156676-Prosthesis-Related Infections,
pubmed-meshheading:8156676-Reoperation,
pubmed-meshheading:8156676-Retrospective Studies
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pubmed:year |
1994
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pubmed:articleTitle |
Treatment of the infected total hip arthroplasty with a two-stage reimplantation protocol.
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pubmed:affiliation |
Department of Orthopaedic Surgery, UCLA School of Medicine 90024.
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pubmed:publicationType |
Journal Article
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