Linked Life Data

8155406

Source:http://linkedlifedata.com/resource/pubmed/id/8155406

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-5-19
pubmed:abstractText
The study was performed to reveal the detailed distribution profiles of fluoride in three different kinds of rat bone--humerus, vertebral arch, and parietal bone--and to compare this with the histological appearance of each bone type. Two groups of Wistar rats were provided water ad libitum containing 0 and 100 ppm fluoride, respectively, for 24 weeks. The fluoride distribution profiles across the bone of the three different bones from the outer to the inner surface were determined by means of an abrasive micro-sampling technique. In control animals, both humerus and parietal bones showed higher concentrations at the periosteal and endosteal surfaces, while the vertebral arch showed additional high levels in the middle (containing trabecular bone) of the tissue. In exposed animals, fluoride levels increased greatly in all three bone types. The vertebral and parietal fluoride distribution profiles were relatively unchanged, although humerus fluoride increased from periosteum to endosteum. The differences in fluoride distribution profiles were apparently related to the histological appearances of these bones. The surface area of bone available and the extent of vascularity appear to affect fluoride uptake.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
8756-3282
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
835-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Distribution profiles of fluoride in three different kinds of rat bones.
pubmed:affiliation
Department of Preventive Dentistry and Dental Public Health, School of Dentistry, University of Leeds, Clarendon Way, UK.
pubmed:publicationType
Journal Article, Comparative Study