| pubmed-article:815432 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:815432 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:815432 | lifeskim:mentions | umls-concept:C0237401 | lld:lifeskim |
| pubmed-article:815432 | lifeskim:mentions | umls-concept:C0009491 | lld:lifeskim |
| pubmed-article:815432 | lifeskim:mentions | umls-concept:C0162801 | lld:lifeskim |
| pubmed-article:815432 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:815432 | pubmed:dateCreated | 1976-6-2 | lld:pubmed |
| pubmed-article:815432 | pubmed:abstractText | Amino terminal sequence analyses were performed on the H and L chains of the idiotypically related IgMlambda and IgGkappa paraproteins isolated from the sera of a patient, Br. The N-terminal 41 residues of the Br k-chain belonged to the Vkiii subgroup, and L chains derived from BrIgMlambda revealed a blocked N-terminus characteristics of lambda-chains. Comparative sequence analysis of the Br mu- and gamma-chains indicated that, although both possessed an unblocked N-terminal glutamic acid, the respective VH regions belonged to seperate subgroups. The N-terminal 27 residues of the Br mu-chain reflected a typical VHiii subgroup sequence. The Br gamma-chain sequence demonstrated a VHI pattern with an unblocked N-terminus. These structural data stand in contrast to previously reported serologic evidence, which indicated that the BrIgMlambda and BrIgGkappa proteins possessed highly similar Vh-associated idiotypic determinants. Final interpretation of these findings of similar Vh idiotypic determinants expressed by H chains belonging to seperate Vh subgroups must await complete sequence analysis of hypervariable segments of the Br gamma- and mu-chains. | lld:pubmed |
| pubmed-article:815432 | pubmed:language | eng | lld:pubmed |
| pubmed-article:815432 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:815432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:815432 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:815432 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:815432 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:815432 | pubmed:author | pubmed-author:HopperJ EJE | lld:pubmed |
| pubmed-article:815432 | pubmed:author | pubmed-author:NoyesCC | lld:pubmed |
| pubmed-article:815432 | pubmed:author | pubmed-author:HeinriksonRR | lld:pubmed |
| pubmed-article:815432 | pubmed:author | pubmed-author:KesselJ WJW | lld:pubmed |
| pubmed-article:815432 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:815432 | pubmed:volume | 116 | lld:pubmed |
| pubmed-article:815432 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:815432 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:815432 | pubmed:pagination | 743-6 | lld:pubmed |
| pubmed-article:815432 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-H... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-A... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-I... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-I... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-I... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-I... | lld:pubmed |
| pubmed-article:815432 | pubmed:meshHeading | pubmed-meshheading:815432-I... | lld:pubmed |
| pubmed-article:815432 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:815432 | pubmed:articleTitle | Comparative studies on monotypic IgMlamba and IgGkappa from an individual patient. II. Amino-terminal sequence analyses. | lld:pubmed |
| pubmed-article:815432 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:815432 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:815432 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:815432 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:815432 | lld:pubmed |
