Linked Life Data

8152621

Source:http://linkedlifedata.com/resource/pubmed/id/8152621

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-5-9
pubmed:abstractText
Layer V pyramidal neurons in the occipital part of the rat cerebral cortex project to both the cervical spinal cord and the tectum early in postnatal development. The occipito-spinal projection is transient and is subsequently withdrawn, while a permanent connection is maintained with the tectum. The withdrawal of the transient occipital corticospinal axons may be due to their inability to respond to target-derived influences. In the current study we co-cultured explants of the occipital cortex and cervical spinal gray matter or tectum in 3-D collagen gels. Directional growth of the cortical axons towards either the cervical spinal gray or tectal explant was observed. This indicates that the failure of neurons located in the occipital cortex to maintain collaterals within the spinal cord in vivo is not due to their inability to respond to a target-derived factor, but must be regulated by other extrinsic factors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Transient projections from rat occipital cortex are able to respond to a spinal target derived diffusible factor in vitro.
pubmed:affiliation
Department of Anatomy and Cell Biology, Georgetown University School of Medicine, Washington, DC.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S.