Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-5-9
pubmed:abstractText
We tested afferent fibres isolated from the saphenous nerve for their responses to mechanical, osmotic and chemical stimuli applied to a vascularly isolated segment of the saphenous vein in the rat. Fifteen units were excited by local mechanical stimulation and many of them were also activated by distension of the venous segment, however exclusively by presumably noxious pressures. Most mechanosensitive fibres were excited by one of the three pain-producing substances, hyperosmotic saline (HS), potassium chloride (KCl) and bradykinin. Three fibres which were insensitive to mechanical stimulation, responded to injection of HS or KCl into the venous segment. We conclude that the venous afferents most likely have nociceptive function. Most are considered to be polymodal.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
175-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Receptive properties of afferent nerve fibres associated with the rat saphenous vein.
pubmed:affiliation
Physiologisches Institut der Universität, Christian-Albrechts-Universität zu Kiel, FRG.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't