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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1994-5-6
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pubmed:abstractText |
The search to identify HIV-associated molecules with superantigenic properties has focussed on demonstration of T cell receptor V beta subset-specific perturbations in HIV-infected patients. In this report, the V beta repertoire of two HIV patients was studied in lymph nodes, where HIV-1 replication is the most intense, and compared to the repertoire found in peripheral blood. Use of this fully MHC-compatible system has allowed identification of a small, partly overlapping set of V beta determinants which appear significantly perturbed in HIV-1 infection. These results are consistent with the presence of an HIV-associated superantigen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0887-6924
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S95-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8152314-Adult,
pubmed-meshheading:8152314-Cells, Cultured,
pubmed-meshheading:8152314-HIV,
pubmed-meshheading:8152314-HIV Infections,
pubmed-meshheading:8152314-Humans,
pubmed-meshheading:8152314-Lymphoid Tissue,
pubmed-meshheading:8152314-Male,
pubmed-meshheading:8152314-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:8152314-Superantigens
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pubmed:year |
1994
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pubmed:articleTitle |
Comparative analysis of the T cell receptor V beta repertoire in various lymphoid tissues from HIV-infected patients: evidence for an HIV-associated superantigen.
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pubmed:affiliation |
Laboratoire d'Immunologie, Institut de Recherches Cliniques de Montréal, Québec, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study
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