| pubmed-article:814976 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0027575 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0032594 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:814976 | lifeskim:mentions | umls-concept:C0621958 | lld:lifeskim |
| pubmed-article:814976 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:814976 | pubmed:dateCreated | 1976-6-2 | lld:pubmed |
| pubmed-article:814976 | pubmed:abstractText | The purified high molecular weight serogroup Y meningococcal polysaccharide contains equimolar proportions of D-glucose and N-acetylneuraminic acid and is partially O-acetylated. Carbon-13 nuclear magnetic resonance (NMR) studies, together with other chemical data, have indicated that the polysaccharide is linked only at C-6 of the D-glucose and C-4 of the sialic acid residues, all the linkages being in the alpha-configuration. The 13CNMR data also indicated that the Y polysaccharide is composed of an alternating sequence of these two different residues, and this was confirmed by its autohydrolysis where the major product was 4-O-alpha-D-glucopyranosyl-beta-D-N-acetylneuraminic acid. The W-135 polysaccharide differs from that of Y only in the absence of O-acetylation and in the configuration of one hydroxyl group of the disaccharide repeating unit. In this case autohydrolysis yielded 4-O-alpha-D-galactopyranosyl-beta-D-N-acetylneuraminic acid as the major product. Structural evidence indicates that the BO and Y polysaccharides are identical. Methanolysis of the Y polysaccharide yielded in addition to the methyl glycosides of glucose and sialic acid, a 9-O-acetyl derivative of the latter. This derivative was formed during the re-N-acetylation process and its formation was mainly due to the presence of sodium ions in the original polysaccharide. | lld:pubmed |
| pubmed-article:814976 | pubmed:language | eng | lld:pubmed |
| pubmed-article:814976 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:814976 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:814976 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:814976 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:814976 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:814976 | pubmed:issn | 0008-4018 | lld:pubmed |
| pubmed-article:814976 | pubmed:author | pubmed-author:SmithI CIC | lld:pubmed |
| pubmed-article:814976 | pubmed:author | pubmed-author:MartinAA | lld:pubmed |
| pubmed-article:814976 | pubmed:author | pubmed-author:Bhattacharjee... | lld:pubmed |
| pubmed-article:814976 | pubmed:author | pubmed-author:JenningsH JHJ | lld:pubmed |
| pubmed-article:814976 | pubmed:author | pubmed-author:KennyC PCP | lld:pubmed |
| pubmed-article:814976 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:814976 | pubmed:volume | 54 | lld:pubmed |
| pubmed-article:814976 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:814976 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:814976 | pubmed:pagination | 1-8 | lld:pubmed |
| pubmed-article:814976 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
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| pubmed-article:814976 | pubmed:meshHeading | pubmed-meshheading:814976-S... | lld:pubmed |
| pubmed-article:814976 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:814976 | pubmed:articleTitle | Structural determination of the polysaccharide antigens of Neisseria meningitidis serogroups Y, W-135, and BO1. | lld:pubmed |
| pubmed-article:814976 | pubmed:publicationType | Journal Article | lld:pubmed |
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