Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0001721,
umls-concept:C0008976,
umls-concept:C0012155,
umls-concept:C0016017,
umls-concept:C0085862,
umls-concept:C0151744,
umls-concept:C0302523,
umls-concept:C0427579,
umls-concept:C0441509,
umls-concept:C0596192,
umls-concept:C0700325,
umls-concept:C1299583,
umls-concept:C1519104,
umls-concept:C1549571,
umls-concept:C1608386
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pubmed:issue |
4
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pubmed:dateCreated |
1994-5-4
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pubmed:abstractText |
We served a low-fat (28% of energy), high-fiber (3.3 g/MJ) diet according to Nordic nutrition recommendations (Rec diet), and a high-fat diet (39% of energy) corresponding to the average Danish diet (Dane diet) for periods of 2 wk in a randomized crossover study of 21 healthy middle-aged individuals. The Rec diet resulted in lower serum concentrations of low-density-lipoprotein (LDL) cholesterol (medians: 2.77 vs 3.04 mmol/L, P < 0.001) and high-density-lipoprotein (HDL) cholesterol (1.08 vs 1.24 mmol/L, P < 0.001), and higher fasting triglycerides (1.11 vs 0.86 mmol/L, P = 0.04) than did the Dane diet. Furthermore, the Rec diet lowered plasma factor VII coagulant activity (FVIIc) (88% vs 96%, P = 0.002) and raised plasma fibrinolytic activity. Our observations indicate that a low-fat, high-fiber diet may not only reduce the atherogenic but also the thrombogenic tendency of an individual compared with a diet corresponding to the average Danish diet.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
935-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8147341-Blood Coagulation,
pubmed-meshheading:8147341-Dietary Fats,
pubmed-meshheading:8147341-Dietary Fiber,
pubmed-meshheading:8147341-Female,
pubmed-meshheading:8147341-Fibrinolysis,
pubmed-meshheading:8147341-Humans,
pubmed-meshheading:8147341-Lipids,
pubmed-meshheading:8147341-Male,
pubmed-meshheading:8147341-Middle Aged,
pubmed-meshheading:8147341-Myocardial Ischemia
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pubmed:year |
1994
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pubmed:articleTitle |
Low-fat, high-fiber diet favorably affects several independent risk markers of ischemic heart disease: observations on blood lipids, coagulation, and fibrinolysis from a trial of middle-aged Danes.
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pubmed:affiliation |
Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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