Linked Life Data

8147044

Source:http://linkedlifedata.com/resource/pubmed/id/8147044

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-5-3
pubmed:abstractText
Disorders of carbohydrate metabolism in pregnancy are often associated with macrosome newborns. There are two methods with different approach for retrospective diagnosis of gestational diabetes (GDM): 1. maternal postnatal oral glucose tolerance test (ppoGTT), 2. determination of cord blood insulin for detection of fetal hyperinsulinism. The presented study deals with the question how often macrosomia is correlated with pathologic cord blood insulin respectively pathologic ppoGTT and if both methods select identical collectives. Cord blood insulin was determined by RIA in 154 newborns with birth weight over the 90th percentile (threshold 15 microU/ml). On the 2nd day p.p. oGTT was performed in 80 women without prenatal diagnosis of GDM (threshold 95, 165, 145, 125 mg%). 37/154 (24%) newborns showed pathologic insulin values. 24/80 (30%) women had pathologic ppoGTT. In 30% of the cases pathologic results of cord blood insulin and ppoGTT selected different collectives: 17/66 pathologic ppoGTT with normal insulin values, 7/14 normal ppoGTT with pathologic insulin values. The only use of ppoGTT would fail in 50% of cases of GDM with proved fetal hyperinsulinism. The determination of cord blood insulin offers the opportunity of direct diagnostics on the child in contrast to maternal ppoGTT. For retrospective diagnosis of macrosomia due to disorders of carbohydrate metabolism determination of cord blood insulin should be given preference to oGTT in puerperium.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-967X
pubmed:author
pubmed:issnType
Print
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
257-61
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:articleTitle
[Postpartum diagnosis of diabetes in pregnancy in fetal macrosomia--comparison of two examinations].
pubmed:affiliation
Krankenhaus Neukölln, Abteilung für Geburtsmedizin, Berlin.
pubmed:publicationType
Journal Article, English Abstract