Linked Life Data

8146657

Source:http://linkedlifedata.com/resource/pubmed/id/8146657

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5156
pubmed:dateCreated
1994-5-3
pubmed:abstractText
The genetic requirements for adaptive mutation in Escherichia coli parallel those for homologous recombination in the RecBCD pathway. Recombination-deficient recA and recB null mutant strains are deficient in adaptive reversion. A hyper-recombinagenic recD strain is hypermutable, and its hypermutation depends on functional recA and recB genes. Genes of subsidiary recombination systems are not required. These results indicate that the molecular mechanism by which adaptive mutation occurs includes recombination. No such association is seen for spontaneous mutation in growing cells.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
264
pubmed:geneSymbol
recA, recB, recC, recD
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
258-60
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Recombination in adaptive mutation.
pubmed:affiliation
Department of Genetics, University of Alberta, Edmonton, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't