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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1994-5-3
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pubmed:abstractText |
Walker 256 carcinosarcoma cells (1 x 10(4)) were injected into the right thigh muscle of Sprague-Dawley rats (125 g) consuming isoenergetic (200 g fat/kg) diets containing 20, 100 and 200 g maize oil/kg and 180, 100 or 0 g hydrogenated lard/kg respectively. Ten rats from each dietary regimen were killed every 4th day. Tumours grew rapidly from day 0 to day 8 post-transplant regardless of dietary regimen. However, after 8 d more tumours regressed and there were fewer deaths in animals fed on 200 g maize oil/kg compared with animals fed on 20 or 100 g maize oil/kg. Linoleic acid (LA) levels were higher in phospholipids (PL) of growing tumours than in regressing tumours whereas arachidonic acid levels in PL were lower in growing tumours indicating a possible alteration in the desaturation and elongation of LA. Serum prostaglandin E2 levels were slightly lower in rats with regressing tumours than in rats with growing tumours.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Corn Oil,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Linoleic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-1145
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8142339-Animals,
pubmed-meshheading:8142339-Arachidonic Acids,
pubmed-meshheading:8142339-Carcinoma 256, Walker,
pubmed-meshheading:8142339-Corn Oil,
pubmed-meshheading:8142339-Diet,
pubmed-meshheading:8142339-Dinoprostone,
pubmed-meshheading:8142339-Linoleic Acids,
pubmed-meshheading:8142339-Lipid Metabolism,
pubmed-meshheading:8142339-Neoplasm Regression, Spontaneous,
pubmed-meshheading:8142339-Neoplasm Transplantation,
pubmed-meshheading:8142339-Phospholipids,
pubmed-meshheading:8142339-Random Allocation,
pubmed-meshheading:8142339-Rats,
pubmed-meshheading:8142339-Rats, Sprague-Dawley
|
pubmed:year |
1994
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pubmed:articleTitle |
Dietary level of maize oil affects growth and lipid composition of Walker 256 carcinosarcoma.
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pubmed:affiliation |
Lipids Research Group, University of California, Davis 95616.
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pubmed:publicationType |
Journal Article,
Comparative Study
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