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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1976-4-30
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pubmed:abstractText |
Lymphocytes were investigated for both Fc- and complement-rosette-forming cell activities. At least three subpopulations differing in the relative activities of the Fc and complement receptors have been disclosed. In human tonsils a subpopulation of B lymphocytes had a higher complement-receptor activity than Fc-receptor activity. In contrast, the peripheral cells from a patient with a lymphoma and another with an undiagnosed lymphocytic disease contained a population of B lymphocytes with higher Fc-receptor than complement- receptor activity. In three patients with chronic lymphocytic leukemia, B lymphocytes contained both Fc- and complement-receptor activities. No differences between complement- and Fc-receptor activities were evident in normal human peripheral blood. Fc-receptor, but not complement-receptor activity was inhibited by 2% gamma-globulin, or 8 X 10(3) M iodoacetate. EDTA at 1.7 X 19(-2) M concentration has no effect upon Fc- or complement-rosette-forming cells. The activity of both receptors was diminished at 4 degrees C.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Complement System Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Edetic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Fc Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Iodoacetates,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, B-Cell,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Drug
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pubmed:status |
MEDLINE
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pubmed:issn |
0020-5915
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
488-96
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:814104-B-Lymphocytes,
pubmed-meshheading:814104-Complement System Proteins,
pubmed-meshheading:814104-Edetic Acid,
pubmed-meshheading:814104-Humans,
pubmed-meshheading:814104-Immune Adherence Reaction,
pubmed-meshheading:814104-Immunoglobulin Fc Fragments,
pubmed-meshheading:814104-Iodoacetates,
pubmed-meshheading:814104-Leukemia, Lymphoid,
pubmed-meshheading:814104-Lymphoma,
pubmed-meshheading:814104-Palatine Tonsil,
pubmed-meshheading:814104-Receptors, Antigen, B-Cell,
pubmed-meshheading:814104-Receptors, Drug,
pubmed-meshheading:814104-Temperature
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pubmed:year |
1976
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pubmed:articleTitle |
Fc- and complement-receptor rosette-forming cell ratios in human tonsils and peripheral blood.
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pubmed:publicationType |
Journal Article
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