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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6467
|
| pubmed:dateCreated |
1994-4-28
|
| pubmed:abstractText |
A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament. Discrete stepwise movements averaging 11 nm were seen under conditions of low load, and single force transients averaging 3-4 pN were measured under isometric conditions. The magnitudes of the single forces and displacements are consistent with predictions of the conventional swinging-crossbridge model of muscle contraction.
|
| pubmed:grant | |
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0028-0836
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
10
|
| pubmed:volume |
368
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
113-9
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:8139653-Actins,
pubmed-meshheading:8139653-Adenosine Triphosphate,
pubmed-meshheading:8139653-Animals,
pubmed-meshheading:8139653-Biomechanics,
pubmed-meshheading:8139653-Feedback,
pubmed-meshheading:8139653-Myosin Subfragments,
pubmed-meshheading:8139653-Myosins,
pubmed-meshheading:8139653-Rabbits
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Single myosin molecule mechanics: piconewton forces and nanometre steps.
|
| pubmed:affiliation |
Department of Biochemistry, Beckman Center, Stanford University School of Medicine, California 94305.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|