|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1994-4-20
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|
pubmed:abstractText |
Morphologically similar soft-tissue sarcomas may behave in very different fashions, making it difficult to predict clinical outcomes and to properly design therapeutic interventions. In a preliminary study, we observed that TP53 mutations and nuclear overexpression of p53 protein were frequent events in soft-tissue sarcoma, and we noticed an association between p53-positive phenotype and poor clinical outcome.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0027-8874
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
6
|
|
pubmed:volume |
86
|
|
pubmed:geneSymbol |
p53
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
549-54
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:8133539-Adult,
pubmed-meshheading:8133539-Antibodies, Monoclonal,
pubmed-meshheading:8133539-Gene Expression,
pubmed-meshheading:8133539-Humans,
pubmed-meshheading:8133539-Immunohistochemistry,
pubmed-meshheading:8133539-Ki-67 Antigen,
pubmed-meshheading:8133539-Neoplasm Proteins,
pubmed-meshheading:8133539-Nuclear Proteins,
pubmed-meshheading:8133539-Phenotype,
pubmed-meshheading:8133539-Predictive Value of Tests,
pubmed-meshheading:8133539-Prognosis,
pubmed-meshheading:8133539-Sarcoma,
pubmed-meshheading:8133539-Survival Analysis,
pubmed-meshheading:8133539-Tumor Suppressor Protein p53
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Prognostic implications of p53 nuclear overexpression and high proliferation index of Ki-67 in adult soft-tissue sarcomas.
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|
pubmed:affiliation |
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
