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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-4-15
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pubmed:abstractText |
The effect of lanthanide ions (Ln3+) and their coordination compounds of diethylenetriamine pentaacetic acid (DTPA) on the phase behavior of dipalmitoylphosphatidylcholine (DPPC) multi-lamellar liposomes has been studied by differential scanning calorimetry (DSC), Raman spectroscopy, and freeze-fracture electron microscopic techniques. The displacement of Ca2+ binding on DPPC liposomes by lanthanide ions was also studied. The results show that the binding degree of four kinds of chloride salts with DPPC liposomes is: YbCl3 > GdCl3 > LaCl3 > CaCl2. Lanthanide ions increase the phase transition temperature of DPPC liposomes and decrease the membrane fluidity. Freeze-fracture electron microscopic results show that La3+ enhances the order of DPPC membrane. The effect of coordination compounds of lanthanides with DTPA on the phase behavior of DPPC liposomes is smaller than that of their chlorides. La3+, Gd3+, and Yb3+, can displace Ca2+ binding on DPPC liposomes, but there coordination compounds of DTPA can hardly displace Ca2+. Raman spectroscopic results show that a very slight effect in lateral packing order of DPPC liposomes was observed at various concentrations of lanthanides.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,2-Dipalmitoylphosphatidylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Cations,
http://linkedlifedata.com/resource/pubmed/chemical/Gadolinium,
http://linkedlifedata.com/resource/pubmed/chemical/Lanthanum,
http://linkedlifedata.com/resource/pubmed/chemical/Liposomes,
http://linkedlifedata.com/resource/pubmed/chemical/Metals, Rare Earth,
http://linkedlifedata.com/resource/pubmed/chemical/Pentetic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Ytterbium
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0162-0134
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-49
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8133251-1,2-Dipalmitoylphosphatidylcholine,
pubmed-meshheading:8133251-Binding, Competitive,
pubmed-meshheading:8133251-Calcium,
pubmed-meshheading:8133251-Calorimetry, Differential Scanning,
pubmed-meshheading:8133251-Cations,
pubmed-meshheading:8133251-Freeze Fracturing,
pubmed-meshheading:8133251-Gadolinium,
pubmed-meshheading:8133251-Lanthanum,
pubmed-meshheading:8133251-Liposomes,
pubmed-meshheading:8133251-Metals, Rare Earth,
pubmed-meshheading:8133251-Microscopy, Electron,
pubmed-meshheading:8133251-Pentetic Acid,
pubmed-meshheading:8133251-Spectrum Analysis, Raman,
pubmed-meshheading:8133251-Ytterbium
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pubmed:year |
1994
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pubmed:articleTitle |
Effect of lanthanide ions on the phase behavior of dipalmitoylphosphatidylcholine multilamellar liposomes.
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pubmed:affiliation |
Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Academia Sinica, P. R. China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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