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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1994-4-18
|
| pubmed:abstractText |
Adenovirus infections in 201 bone marrow transplant (BMT) recipients over 4 years were retrospectively reviewed. Forty-two patients (20.9%) had positive adenovirus cultures after BMT. There was a higher incidence of adenovirus infections in pediatric patients than in adults (31.3% vs. 13.6%, P = .003). In addition, the time of onset of adenovirus infection after transplant was earlier in pediatric patients (mean, < 30 days) than in adults (> 90 days). Adenovirus type 35 was the most common serotype identified. One-third of adenovirus-positive patients had definite or probable adenovirus disease. Moderate to severe acute graft-versus-host disease and isolation of adenovirus from two or more sites were significant risk factors for adenovirus disease. This report documents a higher incidence of both adenovirus infection and disease than do previous studies. Adenovirus may emerge as a more frequent pathogen as more high-risk BMT transplants are done.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
169
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
775-81
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8133091-Adenovirus Infections, Human,
pubmed-meshheading:8133091-Adenoviruses, Human,
pubmed-meshheading:8133091-Adolescent,
pubmed-meshheading:8133091-Adult,
pubmed-meshheading:8133091-Age Factors,
pubmed-meshheading:8133091-Anemia, Aplastic,
pubmed-meshheading:8133091-Bone Marrow Transplantation,
pubmed-meshheading:8133091-Child,
pubmed-meshheading:8133091-Child, Preschool,
pubmed-meshheading:8133091-Cohort Studies,
pubmed-meshheading:8133091-Female,
pubmed-meshheading:8133091-Graft vs Host Disease,
pubmed-meshheading:8133091-Humans,
pubmed-meshheading:8133091-Incidence,
pubmed-meshheading:8133091-Infant,
pubmed-meshheading:8133091-Leukemia,
pubmed-meshheading:8133091-Lymphoma,
pubmed-meshheading:8133091-Male,
pubmed-meshheading:8133091-Middle Aged,
pubmed-meshheading:8133091-Myelodysplastic Syndromes,
pubmed-meshheading:8133091-Retrospective Studies,
pubmed-meshheading:8133091-Risk Factors,
pubmed-meshheading:8133091-Serotyping,
pubmed-meshheading:8133091-Time Factors
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Increasing incidence of adenovirus disease in bone marrow transplant recipients.
|
| pubmed:affiliation |
Department of Medicine, Medical College of Wisconsin, Milwaukee County Medical Center, Children's Hospital of Wisconsin, Milwaukee 53226.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|