Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1978-12-27
pubmed:abstractText
A fast transport of noradrenaline (NA) at a velocity of 392 mm/day was found in cat peroneal nerve using a double-ligation technique and a new sensitive radioenzymatic assay for catecholamines. The velocity of transport of NA is sufficiently close to that of 410 mm/day found for labelled proteins and polypeptides to be considered as moving down within the nerve fibres by the same transport mechanism. In addition, dopamine (DA) was also found to be moved down by anterograde transport at a fast, but not well defined, rate. Disulfiram, a dopamine-beta-hydroxylase inhibiting agent, reduced NA levels and increased DA both in control nerve segments and within the portion of the nerve isolated by ligations where NA-containing densecore vesicles are present. The results are considered to support a dynamic turnover of NA and DA in the dense-core vesicles as they are trasnported in the axons.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-1180086, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-1278114, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-13600373, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-14174431, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4100392, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4111802, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4117554, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4119621, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4123797, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4267963, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4303920, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4402308, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4564602, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-4722575, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-52690, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-55480, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5682511, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5768206, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5866619, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5904157, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5937401, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5937402, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-5967594, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-6081281, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-69015, http://linkedlifedata.com/resource/pubmed/commentcorrection/81300-69016
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
281
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
315-24
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Fast axoplasmic transport of noradrenaline and dopamine in mammalian peripheral nerve.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.