Linked Life Data

8125310

Source:http://linkedlifedata.com/resource/pubmed/id/8125310

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-4-14
pubmed:databankReference
pubmed:abstractText
cDNAs encoding human family-IV phosphodiesterase, subtype D (hPDE IVD) were isolated from a human heart cDNA library. The overlapping cDNAs encode a polypeptide of 604 amino acids (aa) with a predicted M(r) of 68,502, which is 91.4% identical to the rat homolog, rPDE IVD. hPDE IVD produced in Escherichia coli was inhibited by rolipram. Expression of the hPDE IVD mRNA is widespread in human tissues and most abundant in skeletal muscle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0378-1119
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
138
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:8125310-3',5'-Cyclic-AMP Phosphodiesterases, pubmed-meshheading:8125310-Amino Acid Sequence, pubmed-meshheading:8125310-Animals, pubmed-meshheading:8125310-Base Sequence, pubmed-meshheading:8125310-Cloning, Molecular, pubmed-meshheading:8125310-DNA, Complementary, pubmed-meshheading:8125310-Escherichia coli, pubmed-meshheading:8125310-Female, pubmed-meshheading:8125310-Gene Expression, pubmed-meshheading:8125310-Gene Library, pubmed-meshheading:8125310-Humans, pubmed-meshheading:8125310-Isoenzymes, pubmed-meshheading:8125310-Molecular Sequence Data, pubmed-meshheading:8125310-Multigene Family, pubmed-meshheading:8125310-Muscles, pubmed-meshheading:8125310-Myocardium, pubmed-meshheading:8125310-Organ Specificity, pubmed-meshheading:8125310-Phosphodiesterase Inhibitors, pubmed-meshheading:8125310-Polymerase Chain Reaction, pubmed-meshheading:8125310-Pregnancy, pubmed-meshheading:8125310-Pyrrolidinones, pubmed-meshheading:8125310-RNA, Messenger, pubmed-meshheading:8125310-Rats, pubmed-meshheading:8125310-Rolipram, pubmed-meshheading:8125310-Sequence Homology, Amino Acid, pubmed-meshheading:8125310-Sequence Homology, Nucleic Acid
pubmed:year
1994
pubmed:articleTitle
Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD).
pubmed:affiliation
Syntex Discovery Research, Institute of Bio-Organic Chemistry, Palo Alto, CA 94304.
pubmed:publicationType
Journal Article, Comparative Study