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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-4-14
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pubmed:databankReference |
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pubmed:abstractText |
We cloned and characterized two allelic variants of the gene for the Bombyx mori prothoracicotropic hormone (PTTH), a homodimeric 30-kDa brain secretory protein. These PTTH genes contain five exons that encode a precursor protein consisting of 224 amino acid residues whose C-terminal 109 residues represent the PTTH subunit. The Bombyx haploid genome contains a single copy of the PTTH gene. The major site of PTTH expression is the brain but expression at a very low level occurs in the gut. One Bombyx brain at day 0 of the fifth larval instar contained 2.4-2.8 pg PTTH mRNA, and this amount did not change markedly during larval-pupal development.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0014-2956
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
220
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
633-43
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pubmed:dateRevised |
2007-7-23
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pubmed:meshHeading |
pubmed-meshheading:8125124-Amino Acid Sequence,
pubmed-meshheading:8125124-Animals,
pubmed-meshheading:8125124-Base Sequence,
pubmed-meshheading:8125124-Blotting, Northern,
pubmed-meshheading:8125124-Blotting, Southern,
pubmed-meshheading:8125124-Bombyx,
pubmed-meshheading:8125124-Brain,
pubmed-meshheading:8125124-Cloning, Molecular,
pubmed-meshheading:8125124-DNA,
pubmed-meshheading:8125124-DNA Primers,
pubmed-meshheading:8125124-Gene Expression,
pubmed-meshheading:8125124-Genes, Insect,
pubmed-meshheading:8125124-Genomic Library,
pubmed-meshheading:8125124-Insect Hormones,
pubmed-meshheading:8125124-Macromolecular Substances,
pubmed-meshheading:8125124-Molecular Sequence Data,
pubmed-meshheading:8125124-Neuropeptides,
pubmed-meshheading:8125124-Oligonucleotide Probes,
pubmed-meshheading:8125124-Polymerase Chain Reaction,
pubmed-meshheading:8125124-RNA, Messenger,
pubmed-meshheading:8125124-Restriction Mapping,
pubmed-meshheading:8125124-Transcription, Genetic
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pubmed:year |
1994
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pubmed:articleTitle |
Structure and expression of the gene for the prothoracicotropic hormone of the silkmoth Bombyx mori.
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pubmed:affiliation |
Department of Biology, School of Science, Nagoya University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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