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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1994-4-13
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pubmed:abstractText |
Balloon angioplasty of atherosclerotic arteries results in activation of the coagulation cascade. Several coagulation factors, including factor Xa and thrombin, are mitogenic for vascular smooth muscle cells in vitro and thus may play a role in restenosis after balloon angioplasty. Specific inhibition of factor Xa can be achieved with recombinant antistasin (rATS) or tick anticoagulant peptide (rTAP). We hypothesized that inhibition of Xa would limit restenosis after balloon angioplasty in an atherosclerotic rabbit model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1262-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8124815-Angioplasty, Balloon,
pubmed-meshheading:8124815-Animals,
pubmed-meshheading:8124815-Arteriosclerosis,
pubmed-meshheading:8124815-Arthropod Proteins,
pubmed-meshheading:8124815-Factor Xa,
pubmed-meshheading:8124815-Femoral Artery,
pubmed-meshheading:8124815-Invertebrate Hormones,
pubmed-meshheading:8124815-Leeches,
pubmed-meshheading:8124815-Male,
pubmed-meshheading:8124815-Peptides,
pubmed-meshheading:8124815-Rabbits,
pubmed-meshheading:8124815-Recurrence,
pubmed-meshheading:8124815-Ticks,
pubmed-meshheading:8124815-Time Factors
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pubmed:year |
1994
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pubmed:articleTitle |
Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.
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pubmed:affiliation |
Cardiovascular Division, University of Virginia School of Medicine, Charlottesville 22908.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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