Linked Life Data

8124473

Source:http://linkedlifedata.com/resource/pubmed/id/8124473

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-4-12
pubmed:abstractText
The migration of metal cations in capillary electrophoresis with indirect UV detection was investigated. A mathematical model was used to relate the electrophoretic mobility of a metal cation with two background electrolyte factors: the pH and the concentration of a complexing agent. Imidazole, which has an electrophoretic mobility close to those of metal cations, was used as the visualization agent, and 2-hydroxyisobutyric acid (HIBA) was used as the complexing agent. Through computer modeling, the electrophoretic mobilities of fourteen metal cations were predicted on the basis of five initial experiments within the factor space of pH and HIBA concentration. Good agreement was observed between the predicted electrophoretic mobilities and the observed values of the metal cations. Subsequently, the separation of a complex mixture of metal cations was successfully optimized. A complete separation of 14 metal cations including alkali, alkaline earth and transition metal(II) cations was achieved within 4 min. In addition, the effectiveness of other visualization agents and complexing agents for the separation of metal cations was examined.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
659
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
459-66
pubmed:dateRevised
2009-1-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Prediction and optimization of the separation of metal cations by capillary electrophoresis with indirect UV detection.
pubmed:affiliation
Department of Chemistry, North Carolina State University, Raleigh 27695.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't