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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1978-12-29
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pubmed:abstractText |
Conditions are described for diazonium linkage of the hapten p-azophenylarsonate (Ar) to mouse lymphocytes for the purpose of induction of syngeneic cytolytic T lymphocytes. These cytolytic effector cells do not lyse target cells that are coupled with an unrelated hapten, trinitrophenyl. Cell lysis can be blocked by the addition of anti-Ar antiserum. Only those target cells that share H-2 K or D end antigens with the stimulating cell population are susceptible to lysis. Several methods were used in an attempt to demonstrate the presence of the Ar cross-reactive idiotype on CTL induced in A/J mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-1767
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1432-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:81234-Animals,
pubmed-meshheading:81234-Azo Compounds,
pubmed-meshheading:81234-Cross Reactions,
pubmed-meshheading:81234-Cytotoxicity, Immunologic,
pubmed-meshheading:81234-Epitopes,
pubmed-meshheading:81234-Histocompatibility Antigens,
pubmed-meshheading:81234-Immunoglobulin Idiotypes,
pubmed-meshheading:81234-Lymphocytes,
pubmed-meshheading:81234-Mice,
pubmed-meshheading:81234-Mice, Inbred BALB C,
pubmed-meshheading:81234-T-Lymphocytes,
pubmed-meshheading:81234-Trinitrobenzenes,
pubmed-meshheading:81234-p-Azobenzenearsonate
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pubmed:year |
1978
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pubmed:articleTitle |
The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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