Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-4-4
pubmed:abstractText
The neuronal growth-associated protein (GAP-43) is widely expressed during embryonic growth and axonal regeneration and has been thought to contribute to synaptic plasticity in adult animals. In contrast to the exclusively presynaptic pattern of GAP-43 immunoreactivity in sympathetic ganglia, GAP-43 intensely and selectively labeled the noradrenergic subpopulation of adult rat adrenal medullary chromaffin cell bodies, a pattern which persisted with adrenal denervation. Adjacent adrenergic islands containing neuropeptide Y and phenylethanolamine-N-methyl transferase immunoreactivity failed to express GAP-43. The immunohistochemical appearance of GAP-43 was qualitatively unchanged in the adrenal medulla of aged and diabetic rats, conditions in which the sympathoadrenal axis is thought to be dysfunctional.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
162
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-33
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Correlation of GAP-43 immunoreactivity with subpopulations of chromaffin cells in rat adrenal medulla.
pubmed:affiliation
Department of Pathology, Washington University School of Medicine, Saint Louis, MO 63110.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.