Linked Life Data

8120744

Source:http://linkedlifedata.com/resource/pubmed/id/8120744

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-4-4
pubmed:abstractText
Neuroanatomical and electrophysiological studies of albino visual pathways have demonstrated that retinogeniculate axons arising from the temporal retina decussate abnormally in the optic chiasm to synapse in the contralateral lateral geniculate nucleus (LGN). Anomalies in the LGN secondarily disrupt normal geniculo-cortical and interhemispheric cortico-cortical (callosal) visual connections. It is not known whether retinogeniculate misrouting affects the size or configuration of the afferent visual pathways in human albinos. We used T1-weighted coronal and sagittal magnetic resonance imaging (MRI) to examine the prechiasmatic intracranial optic nerves, optic chiasm, and corpus callosum in 10 human albinos. In all subjects, these structures were normal in size and configuration. Despite the complex cascade of aberrant central neuronal connections, the human albino visual pathways and their interhemispheric connections appear normal in size and configuration when viewed with MRI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0191-3913
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
382-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Magnetic resonance imaging of the visual pathways in human albinos.
pubmed:affiliation
University of Arkansas for Medical Sciences, Department of Ophthalmology, Little Rock.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't