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rdf:type |
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lifeskim:mentions |
umls-concept:C0008651,
umls-concept:C0009219,
umls-concept:C0017337,
umls-concept:C0024779,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0086418,
umls-concept:C0218111,
umls-concept:C0521324,
umls-concept:C1413064,
umls-concept:C1521007,
umls-concept:C1711351,
umls-concept:C1979844
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pubmed:issue |
9
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|
pubmed:dateCreated |
1994-4-1
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pubmed:abstractText |
Using both chromosomal in situ hybridization and molecular techniques, we report the genetic localization of the gene coding for the alpha 1 subunit of the skeletal slow Ca2+ current channel/DHP receptor gene (Cchl1a3) on human Chromosome (Chr) 1 (1q31-1q32 region) and on mouse Chr 1 (region (F-G)). On the basis of single-strand conformation polymorphism (SSCP-PCR) analysis in an interspecific backcross, we have determined that the Cchl1a3 = mdg (muscular dysgenesis) locus is very closely linked to the myogenin (Myog) locus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0938-8990
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:geneSymbol |
Cchl1a3,
mdg
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
499-503
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8118099-Animals,
pubmed-meshheading:8118099-Base Sequence,
pubmed-meshheading:8118099-Bone and Bones,
pubmed-meshheading:8118099-Calcium Channels,
pubmed-meshheading:8118099-Calcium Channels, L-Type,
pubmed-meshheading:8118099-Chromosome Mapping,
pubmed-meshheading:8118099-Chromosomes, Human, Pair 1,
pubmed-meshheading:8118099-Crosses, Genetic,
pubmed-meshheading:8118099-DNA Primers,
pubmed-meshheading:8118099-Humans,
pubmed-meshheading:8118099-In Situ Hybridization,
pubmed-meshheading:8118099-Mice,
pubmed-meshheading:8118099-Mice, Inbred C57BL,
pubmed-meshheading:8118099-Molecular Sequence Data,
pubmed-meshheading:8118099-Muridae,
pubmed-meshheading:8118099-Muscle Proteins,
pubmed-meshheading:8118099-Polymorphism, Genetic,
pubmed-meshheading:8118099-Receptors, Cholinergic
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pubmed:year |
1993
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pubmed:articleTitle |
The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.
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pubmed:affiliation |
Groupe de Biologie, Développement et Régénération du Système Neuromusculaire, INSERM U. 153, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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