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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1994-3-29
|
| pubmed:abstractText |
We report the first isolation of a unique adduct of pyridoxal 5'-phosphate, 5'-phosphopyridoxyl-D,L-7-azatryptophan, and suggest a new and easier route for synthesis and purification of 5'-phosphopyridoxyl-L-(or -D-)tryptophan. The absorbance and emission spectra of the 7-azatryptophan adduct are distinctly different than those of pyridoxal 5'-phosphate or the tryptophan adduct. We propose that 5'-phosphopyridoxyl-D,L-7-azatryptophan has great potential as an intrinsic probe in optical studies of protein dynamics.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0006-291X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
198
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1007-11
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8117256-Indicators and Reagents,
pubmed-meshheading:8117256-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8117256-Molecular Structure,
pubmed-meshheading:8117256-Proteins,
pubmed-meshheading:8117256-Pyridoxal Phosphate,
pubmed-meshheading:8117256-Spectrophotometry,
pubmed-meshheading:8117256-Tryptophan
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Synthesis and spectral characterization of 5'-phosphopyridoxyl-D,L-7-azatryptophan, a photophysical probe of protein structure and dynamics.
|
| pubmed:affiliation |
Department of Chemistry, Iowa State University, Ames 50011.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|