Linked Life Data

8116092

Source:http://linkedlifedata.com/resource/pubmed/id/8116092

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1994-3-30
pubmed:abstractText
In patients with temporal arteritis and polymyalgia rheumatica, a marked depletion of percentage and number of circulating CD8+ T-lymphocytes are found in most cases. We assessed the diagnostic value of CD8+ levels in a larger group of patients with temporal arteritis and polymyalgia rheumatica before and after treatment with prednisolone and in relation to patients with other medical and rheumatic diseases. Median percentage and number of CD8+ cells in patients with polymyalgia rheumatica were significantly decreased (CD8+% 12.0, CD8+ cells 0.192 x 10(9)/l) compared with 1) controls (CD8+% 23.0, CD8+ cells 0.51 x 10(9)/l), 2) patients with other rheumatic diseases (CD8+% 20.8, CD8+ cells 0.39 x 10(9)/l), 3) patients with other medical diseases (CD8+% 20.6, CD8+ cells 0.46 x 10(9)/l). After 600 days of prednisolone treatment CD8+ values increased significantly (CD8+% 14.5, CD8+ cells 0.324 x 10(9)/l). In a cohort of patients with a low a priori probability of giant cell arteritis (39%), the positive predictive value of a significantly low CD8+ concentration was 51% while the likelihood of no disease with a normal CD8+ value was 71%.
pubmed:language
dan
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0041-5782
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
156
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1137-41
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[CD8+ T-lymphocytes. Evaluation of the diagnostic value in patients with giant cell arteritis].
pubmed:affiliation
Medicinsk afdeling, Randers Centralsygehus.
pubmed:publicationType
Journal Article, English Abstract