Linked Life Data

8111825

Source:http://linkedlifedata.com/resource/pubmed/id/8111825

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-3-31
pubmed:abstractText
1. In a concentration-dependent manner neuropeptide Y was found to be a potent inhibitor of the spontaneous activation of human granulocytes and macrophages as well as Mytilus edulis immunocytes. 2. Neuropeptide Y also inhibited the chemotaxic response of these immunocytes to the chemoattractant f-MLP. 3. Incubation of both the human and the invertebrate immunocytes in f-MLP (10(-9) M) causes "activation" as noted by random locomotion (chemokinesis). Neuropeptide Y also blocked f-MLP-induced chemokinesis. 4. The results suggest that neuropeptide Y may, in addition to other functions, serve as an endogenous regulator of immunocyte function.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0272-4340
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
541-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Neuropeptide Y inhibits human and invertebrate immunocyte chemotaxis, chemokinesis, and spontaneous activation.
pubmed:affiliation
Multidisciplinary Center for the Study of Aging, Old Westbury Neuroscience Research Institute, State University of New York/College at Old Westbury 11568.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't