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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1994-3-24
|
| pubmed:abstractText |
Clinical, laboratory and cardiac catheterization parameters were reviewed in 355 men and 155 women hospitalized at a tertiary care referral center between February 1987 and December 1991 to analyze why women have a higher in-hospital mortality rate than do men after acute myocardial infarction. Hospital mortality was 21.4% in women and 12.1% in men (p = 0.007). In comparison with men, women were older (63.3 +/- 11.9 vs 60.5 +/- 12.6 years; p = 0.023), had more systemic hypertension (46.5 vs 34.4%; p = 0.001) and higher serum total cholesterol levels (211 +/- 51 vs 197 +/- 49 mg/dl; p = 0.0015), sought medical care later (8.9 vs 5.3 hours; p = 0.026), were referred later (47.7 vs 43.7 hours; p = 0.063) and had more shock (34.8 vs 24.2%; p = 0.013). Logistic regression analysis revealed 5 variables predictive of hospital mortality; age > 65 years, diabetes, shock, non-Q-wave infarction, and not undergoing cardiac catheterization. Gender was of borderline significance in predicting hospital mortality. Cardiac catheterization, performed in 88% of women and 87% of men, showed similar rates of 1-, 2- and 3-vessel disease, and similar characteristics of the infarction-related artery. The differences in hospital mortality between men and women are due to a combination of pre- and in-hospitalization factors in women. The excess mortality is not due to differences in disease severity as evaluated by cardiac catheterization information.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
73
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
319-22
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8109543-Age Factors,
pubmed-meshheading:8109543-Aged,
pubmed-meshheading:8109543-Angina Pectoris,
pubmed-meshheading:8109543-Cholesterol,
pubmed-meshheading:8109543-Diabetes Mellitus,
pubmed-meshheading:8109543-Electrocardiography,
pubmed-meshheading:8109543-Female,
pubmed-meshheading:8109543-Forecasting,
pubmed-meshheading:8109543-Heart Catheterization,
pubmed-meshheading:8109543-Hospital Mortality,
pubmed-meshheading:8109543-Humans,
pubmed-meshheading:8109543-Hypertension,
pubmed-meshheading:8109543-Logistic Models,
pubmed-meshheading:8109543-Male,
pubmed-meshheading:8109543-Middle Aged,
pubmed-meshheading:8109543-Missouri,
pubmed-meshheading:8109543-Myocardial Infarction,
pubmed-meshheading:8109543-Referral and Consultation,
pubmed-meshheading:8109543-Retrospective Studies,
pubmed-meshheading:8109543-Sex Factors,
pubmed-meshheading:8109543-Shock,
pubmed-meshheading:8109543-Women's Health
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Causes of higher in-hospital mortality in women than in men after acute myocardial infarction.
|
| pubmed:affiliation |
University of Missouri, Columbia 65212.
|
| pubmed:publicationType |
Journal Article,
Multicenter Study
|