Linked Life Data

8106267

Source:http://linkedlifedata.com/resource/pubmed/id/8106267

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-3-22
pubmed:abstractText
A novel HLA-DPB1 allele (DPB1*/A6) has been identified in West Africa, and the occurrence of the recently reported allele DPB1*4001 (DPB1*BRI-5) in Negroid populations has been confirmed DPB1*WA6 differs from DPB1*0101 by a silent nucleotide exchange at codon position 43 only. It constitutes, thereby, a link to DPB1*1101, *1501, and *2601 and suggests and evolutionary relationship with these alleles. Carrying the same silent mutation, DPB1*1101, *1501, and *2601 may, by recombinations, have evolved from DPB1*WA6. An apparently older evolutionary branch arose directly from DPB1*0101 and comprises the closely related alleles DPB1*2701 and DPB1*4001 reported only from individuals of African descent.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0198-8859
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
123-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
A silent mutation in HLA-DPB1*0101 and its evolutionary implications.
pubmed:affiliation
Department of Molecular Biology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
pubmed:publicationType
Journal Article