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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5 Pt 1
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pubmed:dateCreated |
1993-12-3
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pubmed:abstractText |
Hypertension and other vascular diseases are more prevalent in diabetic patients than in the general population. In humans and in several animal models of diabetes, a disturbance of endothelium-dependent responses has been shown. Oxyhemoglobin is one of the most known modulators of these endothelium-dependent responses. We postulate that high levels of plasmatic glycosylated hemoglobin, a frequent profile in diabetic patients, may be the cause of the disturbance in endothelium-dependent relaxation and/or contraction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2111-6
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8106180-Acetylcholine,
pubmed-meshheading:8106180-Adrenergic alpha-Agonists,
pubmed-meshheading:8106180-Animals,
pubmed-meshheading:8106180-Aorta,
pubmed-meshheading:8106180-Endothelium, Vascular,
pubmed-meshheading:8106180-Hemoglobin A, Glycosylated,
pubmed-meshheading:8106180-Male,
pubmed-meshheading:8106180-Nitric Oxide,
pubmed-meshheading:8106180-Norepinephrine,
pubmed-meshheading:8106180-Rats,
pubmed-meshheading:8106180-Rats, Sprague-Dawley,
pubmed-meshheading:8106180-Vasodilation
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pubmed:year |
1993
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pubmed:articleTitle |
Interference of glycosylated human hemoglobin with endothelium-dependent responses.
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pubmed:affiliation |
Service of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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