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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1993-10-12
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pubmed:abstractText |
[35S]Lanthionine ketimine binds specifically and with high affinity to bovine brain membranes. This binding has been studied in detail. It is reversible, not occurring at an uptake site or at a metabolizing enzyme and depending only weakly from ionic strength; it is affected by thiol reagents. [35S]Lanthionine ketimine specific binding is displaced only by other ketimines and by catecholamines, but not by more selective adrenergic ligands; binding parameters are reported. [3H]Adrenaline but not [3H]dihydroalprenolol is partially displaced by lanthionine ketimine. With bovine brain preparations a significant stimulation of basal adenylate cyclase activity by lanthionine ketimine is observed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
195
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
673-7
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:8103986-Adenylate Cyclase,
pubmed-meshheading:8103986-Amino Acids, Sulfur,
pubmed-meshheading:8103986-Animals,
pubmed-meshheading:8103986-Binding, Competitive,
pubmed-meshheading:8103986-Brain,
pubmed-meshheading:8103986-Cattle,
pubmed-meshheading:8103986-Cell Membrane,
pubmed-meshheading:8103986-Cerebral Cortex,
pubmed-meshheading:8103986-Erythrocyte Membrane,
pubmed-meshheading:8103986-Kinetics,
pubmed-meshheading:8103986-Neurotransmitter Agents,
pubmed-meshheading:8103986-Sulfur Radioisotopes,
pubmed-meshheading:8103986-Turkeys
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pubmed:year |
1993
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pubmed:articleTitle |
Characterization of [35S]lanthionine ketimine specific binding to bovine brain membranes.
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pubmed:affiliation |
Dipartimento di Scienze Biochimiche A. Rossi Fanelli, Università La Sapienza, Roma, Italy.
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pubmed:publicationType |
Journal Article
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