Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1993-7-26
|
pubmed:abstractText |
The endogenous neuropeptide Tyr-MIF-1 (Tyr-Pro-Leu-Gly-amide) has been shown to counteract various opiate actions. In the current study, third ventricular injection of 35 micrograms Tyr-MIF-1 protected by the enzyme inhibitor bestatin precipitated an abstinence syndrome in morphine-dependent rats, but not in opiate-naive rats. The results raise the possibility that Tyr-MIF-1 might participate in opiate dependence and opiate abstinence syndrome.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0006-8993
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
610
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
169-71
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8100171-Animals,
pubmed-meshheading:8100171-Humans,
pubmed-meshheading:8100171-Infant, Newborn,
pubmed-meshheading:8100171-MSH Release-Inhibiting Hormone,
pubmed-meshheading:8100171-Male,
pubmed-meshheading:8100171-Morphine,
pubmed-meshheading:8100171-Morphine Dependence,
pubmed-meshheading:8100171-Rats,
pubmed-meshheading:8100171-Rats, Sprague-Dawley,
pubmed-meshheading:8100171-Substance Withdrawal Syndrome
|
pubmed:year |
1993
|
pubmed:articleTitle |
Tyr-MIF-1 precipitates abstinence syndrome in morphine-dependent rats.
|
pubmed:affiliation |
University of Houston-Clear Lake, TX 77058.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|