Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-5-14
pubmed:abstractText
We have examined the restriction-fragment-length polymorphism (RFLP) of the VNTR region flanking the Ha-ras1 gene in genomic DNA from 348 testicular cancer patients and 343 healthy controls. When DNA samples were digested with MspI/HpaII, Southern blot analysis revealed 24 and 15 different alleles in the cancer and the control group respectively. The frequency of rare alleles among cases was significantly higher than in controls. Patients with bilateral cancer and patients with unilateral cancer below 20 years had significantly higher incidence of rare alleles than patients with unilateral cancer older than 20 years.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0020-7136
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
53
pubmed:geneSymbol
Ha-ras1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
938-40
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Rare Ha-ras1 alleles and predisposition to testicular cancer.
pubmed:affiliation
Department of Toxicology, National Institute of Occupational Health, Oslo, Norway.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't