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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1993-3-30
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pubmed:abstractText |
A survey of 8080 subjects was conducted in Baltimore, examining the association between infection with hantaviruses and renal disease. Two groups (N = 6060) with no known risk factors were selected to establish a baseline antibody prevalence. Overall, antibody prevalence was 0.25%. Seroprevalence increased with age, without sex- or race-related differences. Patients with proteinuria showed the same patterns of infection but were more commonly seropositive (1.46%) than the reference group (OR, 3.23; P < .05). Infection among dialysis patients with end-stage renal disease was 2.76%, significantly higher than in the reference group (OR, 5.03; P < .05). In the proteinuria and the dialysis groups, hantavirus infection was consistently associated with a diagnosis of hypertensive renal disease. The association was unrelated to other chronic renal disease diagnoses. Overall, 6.5% of patients with end-stage renal disease due to hypertension were seropositive for a hantavirus. These data suggest that hantavirus infection is associated with hypertensive renal disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
167
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
614-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8095060-Adult,
pubmed-meshheading:8095060-Age Factors,
pubmed-meshheading:8095060-Antibodies, Viral,
pubmed-meshheading:8095060-Baltimore,
pubmed-meshheading:8095060-Chronic Disease,
pubmed-meshheading:8095060-Female,
pubmed-meshheading:8095060-Hantavirus,
pubmed-meshheading:8095060-Hemorrhagic Fever with Renal Syndrome,
pubmed-meshheading:8095060-Humans,
pubmed-meshheading:8095060-Hypertension, Renal,
pubmed-meshheading:8095060-Kidney Failure, Chronic,
pubmed-meshheading:8095060-Male,
pubmed-meshheading:8095060-Middle Aged,
pubmed-meshheading:8095060-Odds Ratio,
pubmed-meshheading:8095060-Prevalence,
pubmed-meshheading:8095060-Prospective Studies,
pubmed-meshheading:8095060-Proteinuria,
pubmed-meshheading:8095060-Renal Dialysis
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pubmed:year |
1993
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pubmed:articleTitle |
Infection with a ratborne hantavirus in US residents is consistently associated with hypertensive renal disease.
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pubmed:affiliation |
Department of Immunology and Infectious Diseases, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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