Linked Life Data

809410

Source:http://linkedlifedata.com/resource/pubmed/id/809410

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1975-12-20
pubmed:abstractText
To assess early ventilatory responses at the 2 mg/m3 bituminous coal dust standard, 23 cynomolgus monkeys were exposed by inhalation to Pennsylvania and Utah coal dust. Ten controls were utilized. Pennsylvania coal was selected from a field having a high prevalence of coal workers' pneumoconiosis while the Utah coal was selected from a low prevalence area. After 24 mo of exposure, a pattern of pulmonary impairment consistent with peripheral airway obstruction was demonstrated. Reductions were observed in the forced expiratory volume in 1 s, maximum midexpiratory flow rate, and especially maximum expiratory flow at small lung volumes. Hyperinflation (RV/TLC) was observed in both coal treatments; however, no specific lung volumes differed significantly from controls. No differences were found between the Pennsylvania and Utah treatments. Design and specifications for a new hydraulically operated plethysmograph-respirator are included.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-8987
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
444-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Maximum expiratory flow-volume studies on monkeys exposed to bituminous coal dust.
pubmed:publicationType
Journal Article