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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1994-10-20
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pubmed:abstractText |
For many years, the main goal of premedication was prevention of the dangerous side effects sometimes encountered in anesthetics with anticholinergics, antiemetic antihistaminics, and opioids. Because the rules were always preoperative fasting, premedication was administered i.m. Thus, the onset of action was within 15-30 min from administration. In recent years, with the introduction of newer anesthetics with fewer side effects, anxiolysis became the main aim in premedication. Moreover, the oral route became popular since it obviously did not increase the acidity or volume of the gastric content. However, the uptake and thus onset of action of orally administered drugs may take longer and can differ considerably between individual patients. Therefore, the optimum interval between administration and induction of anesthesia remains controversial. The present study was carried out to examine the time course of drug action and the effects of different premedication regimens on the electroencephalogram (EEG).
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-2417
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
431-40
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8092452-Adult,
pubmed-meshheading:8092452-Arousal,
pubmed-meshheading:8092452-Benzodiazepines,
pubmed-meshheading:8092452-Central Nervous System,
pubmed-meshheading:8092452-Electroencephalography,
pubmed-meshheading:8092452-Humans,
pubmed-meshheading:8092452-Image Interpretation, Computer-Assisted,
pubmed-meshheading:8092452-Middle Aged,
pubmed-meshheading:8092452-Pharmacokinetics,
pubmed-meshheading:8092452-Preanesthetic Medication
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pubmed:year |
1994
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pubmed:articleTitle |
[Electroencephalographic demonstration of central nervous system effects of different premedication regimens].
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pubmed:affiliation |
Institut für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial
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