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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-10-20
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pubmed:abstractText |
Blood lymphocytes from patients with eosinophilia are known to produce interleukin-5 (IL-5) with appropriate stimulation in vitro. To determine whether blood lymphocytes from these patients produce IL-5 in vivo, we tested the IL-5 mRNA expression in blood lymphocytes immediately after separation by reverse-transcriptase polymerase chain reaction (RT-PCR) method. We found that lymphocytes from eosinophilic patients expressed IL-5 mRNA, but lymphocytes from normal volunteers did not express the lymphokine. These findings suggest that in patients with eosinophilia, peripheral blood lymphocytes produce IL-5 in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0361-8609
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
69-73
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8092143-Adult,
pubmed-meshheading:8092143-Angiolymphoid Hyperplasia with Eosinophilia,
pubmed-meshheading:8092143-Animals,
pubmed-meshheading:8092143-Antibodies, Helminth,
pubmed-meshheading:8092143-Base Sequence,
pubmed-meshheading:8092143-Cells, Cultured,
pubmed-meshheading:8092143-Child,
pubmed-meshheading:8092143-Culture Media, Conditioned,
pubmed-meshheading:8092143-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8092143-Humans,
pubmed-meshheading:8092143-Interleukin-5,
pubmed-meshheading:8092143-Lymphocytes,
pubmed-meshheading:8092143-Male,
pubmed-meshheading:8092143-Middle Aged,
pubmed-meshheading:8092143-Molecular Sequence Data,
pubmed-meshheading:8092143-Paragonimiasis,
pubmed-meshheading:8092143-Paragonimus,
pubmed-meshheading:8092143-Polymerase Chain Reaction,
pubmed-meshheading:8092143-RNA, Messenger
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pubmed:year |
1994
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pubmed:articleTitle |
IL-5 mRNA expression in blood lymphocytes from patients with Kimura's disease and parasite infection.
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pubmed:affiliation |
Third Department of Internal Medicine, Dokkyo University, School of Medicine, Tochigi, Japan.
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pubmed:publicationType |
Journal Article
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