Linked Life Data

8091656

Source:http://linkedlifedata.com/resource/pubmed/id/8091656

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-10-20
pubmed:abstractText
Bacteriophage phi 6 has a genome of three segments of double-stranded RNA enclosed in a procapsid composed of four different proteins. The preformed procapsid is capable of packaging plus strand transcripts of the genomic segments in an in vitro reaction. The plus strands then serve as templates for in vitro minus strand synthesis. Procapsids that are missing protein P2 are incapable of minus strand synthesis. In this report we show that incubation with a cell extract containing P2 results in particles with normal amounts of attached P2 and with packaging and replicase activity. Particles lacking P7 have reduced replicase activity which can be augmented by incubation with extracts containing P7, but the amount of attached P7 is small.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0042-6822
pubmed:author
pubmed:issnType
Print
pubmed:volume
204
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
251-3
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Reconstitution of active replicase in procapsids of the segmented dsRNA bacteriophage phi 6.
pubmed:affiliation
Department of Microbiology, Public Health Research Institute, New York, New York 10016.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.