rdf:type |
|
lifeskim:mentions |
umls-concept:C0025519,
umls-concept:C0032043,
umls-concept:C0055565,
umls-concept:C0071869,
umls-concept:C0086418,
umls-concept:C0205321,
umls-concept:C0439851,
umls-concept:C1522492,
umls-concept:C1533691,
umls-concept:C1552596,
umls-concept:C1947931,
umls-concept:C2603343
|
pubmed:issue |
5
|
pubmed:dateCreated |
1975-12-11
|
pubmed:abstractText |
The direct metabolism of cholesteryl-sulfate into pregnenolone sulfate is pointed out during in vitro perfusion of the whole organ and incubation of slices. The metabolite so formed represents a significant fraction of the recovered radioactivity. Cholesteryl-sulfate, which may be hydrolyzed into cholesterol, as well, is considered as a possible precursor of placental steroidogenesis and particularly of progesterone. Differences in the cellular permeability depending on the experimental model considered appear again during these experiments.
|
pubmed:language |
fre
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0567-655X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
3
|
pubmed:volume |
280
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
633-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:809159-Cell Membrane Permeability,
pubmed-meshheading:809159-Cholesterol,
pubmed-meshheading:809159-Cholesterol Esters,
pubmed-meshheading:809159-Female,
pubmed-meshheading:809159-Humans,
pubmed-meshheading:809159-Kinetics,
pubmed-meshheading:809159-Perfusion,
pubmed-meshheading:809159-Placenta,
pubmed-meshheading:809159-Pregnancy,
pubmed-meshheading:809159-Pregnenolone,
pubmed-meshheading:809159-Progesterone,
pubmed-meshheading:809159-Sulfates
|
pubmed:year |
1975
|
pubmed:articleTitle |
[Kinetic study of the in vitro penetration and metabolism of cholesterol sulfate in the human placenta : demonstration of a direct formation of pregnenolone sulfate].
|
pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
|