Linked Life Data

8091227

Source:http://linkedlifedata.com/resource/pubmed/id/8091227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5181
pubmed:dateCreated
1994-10-20
pubmed:abstractText
In the last few years there have been rapid advances in developing genetic maps for humans, greatly enhancing our ability to localize and identify genes for inherited disorders. Through the collaborative efforts of three large groups generating microsatellite markers and the efforts of the 110 CEPH collaborators, a comprehensive human linkage map is presented here. It consists of 5840 loci, of which 970 are uniquely ordered, covering 4000 centimorgans on the sex-averaged map. Of these loci, 3617 are polymerase chain reaction-formatted short tandem repeat polymorphisms, and another 427 are genes. The map has markers at an average density of 0.7 centimorgan, providing a resource for ready transference to physical maps and achieving one of the first goals of the Human Genome Project--a comprehensive, high-density genetic map.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
265
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
2049-54
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC).
pubmed:affiliation
Department of Pediatrics, University of Iowa, Iowa City 52245.
pubmed:publicationType
Journal Article