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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-10-19
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pubmed:databankReference |
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pubmed:abstractText |
The gene encoding the human G-protein-coupled inwardly rectifying potassium channel designated GIRK1 (gene symbol, KCNJ3) was mapped to chromosome 2 by analyzing its segregation in a panel of human-hamster somatic cell hybrids. This assignment was confirmed by fluorescence in situ hybridization to metaphase chromosomes, and the gene was further localized to band 2q24.1. A highly informative simple tandem repeat DNA polymorphism of the form (CA)n was identified and used to localize KCNJ3 within the genetic map of the long arm of chromosome 2.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0888-7543
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
21
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pubmed:geneSymbol |
GIRK1,
IRK1,
KCJN1,
KCJN2,
KCNJ3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
254-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8088798-Animals,
pubmed-meshheading:8088798-Base Sequence,
pubmed-meshheading:8088798-Chromosome Mapping,
pubmed-meshheading:8088798-Chromosomes, Human, Pair 2,
pubmed-meshheading:8088798-Cricetinae,
pubmed-meshheading:8088798-GTP-Binding Proteins,
pubmed-meshheading:8088798-Genes,
pubmed-meshheading:8088798-Humans,
pubmed-meshheading:8088798-Hybrid Cells,
pubmed-meshheading:8088798-In Situ Hybridization, Fluorescence,
pubmed-meshheading:8088798-Lod Score,
pubmed-meshheading:8088798-Male,
pubmed-meshheading:8088798-Molecular Sequence Data,
pubmed-meshheading:8088798-Polymorphism, Genetic,
pubmed-meshheading:8088798-Potassium Channels,
pubmed-meshheading:8088798-Receptors, Muscarinic,
pubmed-meshheading:8088798-Repetitive Sequences, Nucleic Acid
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pubmed:year |
1994
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pubmed:articleTitle |
Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism.
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pubmed:affiliation |
Howard Hughes Medical Institute, University of Chicago, Illinois 60637.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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