Linked Life Data

8088458

Source:http://linkedlifedata.com/resource/pubmed/id/8088458

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1994-10-17
pubmed:abstractText
The postponement of human aging is a long-standing aspiration in many cultures, particularly non-Western ones. Renewed interest in this goal is now being shown within the biomedical research context. This interest has probably arisen because several different approaches have yielded dramatic increases in mean and maximum life span in laboratory organisms. Among the cases where aging has been postponed in animal models are the nematode, Caenorhabditis elegans, the common lab fruit fly, Drosophila melanogaster, and the dietarily restricted rodent, both Mus and Rattus. These successes raise the question of whether similar postponement of aging might be achieved in humans. Among the broad research strategies available, five can be delineated: 1) random testing of favorite interventions; 2) searching for genes that can postpone aging among all or most species; 3) study of in vitro mammalian cell cultures; 4) study of dietarily restricted mammals; and 5) selecting mammals for postponed aging. Although all these methods could conceivably lead to the postponement of human aging, they are very different from each other with respect to their degree of uncertainty, cost, and delay.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0892-6638
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
925-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Prospects for postponing human aging.
pubmed:affiliation
Department of Ecology and Evolutionary Biology, School of Biological Sciences, University of California, Irvine 92717.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review