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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1994-10-18
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pubmed:abstractText |
Primary cultures of human gastric epithelial cells were tested for induction of unscheduled DNA synthesis (UDS) by sterigmatocystin (ST) and T-2 toxin. Autoradiographic results indicated that ST (10(-6)-10(-4)M) induced UDS in the presence of S9 activation system. The repair rates were 24-91% (net grains > or = 3) and 2-71% (net grains > or = 5). T-2 toxin did not induce UDS in this study.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1056-9014
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8087430-Animals,
pubmed-meshheading:8087430-Autoradiography,
pubmed-meshheading:8087430-Biotransformation,
pubmed-meshheading:8087430-Cell Division,
pubmed-meshheading:8087430-Cell Survival,
pubmed-meshheading:8087430-Cells, Cultured,
pubmed-meshheading:8087430-DNA,
pubmed-meshheading:8087430-Dose-Response Relationship, Drug,
pubmed-meshheading:8087430-Epithelial Cells,
pubmed-meshheading:8087430-Epithelium,
pubmed-meshheading:8087430-Gastric Mucosa,
pubmed-meshheading:8087430-Humans,
pubmed-meshheading:8087430-Microsomes, Liver,
pubmed-meshheading:8087430-Rats,
pubmed-meshheading:8087430-Sterigmatocystin,
pubmed-meshheading:8087430-T-2 Toxin
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pubmed:year |
1994
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pubmed:articleTitle |
Effects of sterigmatocystin and T-2 toxin on the induction of unscheduled DNA synthesis in primary cultures of human gastric epithelial cells.
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pubmed:affiliation |
Laboratory of Mycotoxicology, Beijing Institute for Cancer Research, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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