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pubmed-article:8085975pubmed:abstractTextSerum carcinoembryonic antigen (CEA) levels in 33 Australian patients with hepatic metastases from colorectal cancer were measured before and after treatment with hepatic cryotherapy and intra-arterial chemotherapy. Pre-operative and monthly postoperative CEA measurements were made and the lowest postoperative reading was recorded as a percentage fall from the pre-operative level. There was a highly significant association between the maximum percentage fall in CEA and survival. A 50% increase in the maximum percentage fall in CEA level was associated with one-tenth the risk of death (95% CI RR 0.03 to 0.32, Cox regression). It is estimated that an increase in the maximum percentage fall in CEA of 50% from 25 to 75% was associated with an increase in the median survival from 240 days to over 2 years.lld:pubmed
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pubmed-article:8085975pubmed:articleTitleCEA reduction after cryotherapy for liver metastases from colon cancer predicts survival.lld:pubmed
pubmed-article:8085975pubmed:affiliationUniversity of New South Wales Department of Surgery, St George Hospital, Kogarah, Sydney, Australia.lld:pubmed
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