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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1994-10-11
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pubmed:abstractText |
Serum carcinoembryonic antigen (CEA) levels in 33 Australian patients with hepatic metastases from colorectal cancer were measured before and after treatment with hepatic cryotherapy and intra-arterial chemotherapy. Pre-operative and monthly postoperative CEA measurements were made and the lowest postoperative reading was recorded as a percentage fall from the pre-operative level. There was a highly significant association between the maximum percentage fall in CEA and survival. A 50% increase in the maximum percentage fall in CEA level was associated with one-tenth the risk of death (95% CI RR 0.03 to 0.32, Cox regression). It is estimated that an increase in the maximum percentage fall in CEA of 50% from 25 to 75% was associated with an increase in the median survival from 240 days to over 2 years.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0004-8682
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
612-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8085975-Antineoplastic Agents,
pubmed-meshheading:8085975-Carcinoembryonic Antigen,
pubmed-meshheading:8085975-Colonic Neoplasms,
pubmed-meshheading:8085975-Colorectal Neoplasms,
pubmed-meshheading:8085975-Combined Modality Therapy,
pubmed-meshheading:8085975-Cryotherapy,
pubmed-meshheading:8085975-Female,
pubmed-meshheading:8085975-Humans,
pubmed-meshheading:8085975-Infusions, Intra-Arterial,
pubmed-meshheading:8085975-Liver Neoplasms,
pubmed-meshheading:8085975-Male,
pubmed-meshheading:8085975-Middle Aged,
pubmed-meshheading:8085975-Regression Analysis,
pubmed-meshheading:8085975-Survival Analysis
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pubmed:year |
1994
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pubmed:articleTitle |
CEA reduction after cryotherapy for liver metastases from colon cancer predicts survival.
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pubmed:affiliation |
University of New South Wales Department of Surgery, St George Hospital, Kogarah, Sydney, Australia.
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pubmed:publicationType |
Journal Article
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